منابع مشابه
quinoline derivatives as potent anticonvulsants
PURPOSE. A new series of substituted quinoline-2(1H)-one and 1,2,4triazolo[4,3-a]-quinoline derivatives were designed and synthesized to meet the structural requirements essential for anticonvulsant properties. METHODS. 4-substituted-phenyl3,4-dihydro-2(1H)-quinolines, 5-substitutedphenyl-4,5-dihydro-1,2,4-triazolo[4,3a]quinolines and 5-substituted-phenyl-4,5-dihydro-1,2,4triazolo-[4,3-a]quinol...
متن کاملFacile synthesis of 5, 6, 7, 8-tetrahydropyrimido [4, 5-b]-quinoline derivatives.
2-Amino-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile (3) was synthesized by treating cyclohexanone (1) with 2-benzylidenemalononitrile (2) in the presence of ammonium acetate. The reactivity of compound 3 towards dimethylformamide dimethyl acetal (DMF-DMA), carbon disulfide, urea, thiourea, formamide, formic acid, acetyl chloride and isothiocyanate were studied. In addition, the antimicr...
متن کاملThe Baylis-Hillman approach to quinoline derivatives.
Baylis-Hillman reactions of 2-nitrobenzaldehydes with various activated alkenes afford adducts that undergo reductive cyclisation to quinoline derivatives. The chemo- and regioselectivity of cyclisation appears to be influenced by the choice of both the substrate and the reagent system, and competing reactions have been observed.
متن کاملMesolite catalyzed one pot synthesis of quinoline-3-carbonitrile derivatives
Natural mesolite type zeolite was collected, modified by sulfuric acid treatment and characterized by using Powder-X ray diffraction (XRD), Scanning electron microscopy (SEM), Energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FT-IR).Temperature programmed ammonia desorption (NH3-TPD), Brunauer-Emmer-Teller (BET) surface area analysis. Modified dealuminat...
متن کاملMesolite catalyzed one pot synthesis of quinoline-3-carbonitrile derivatives
Natural mesolite type zeolite was collected, modified by sulfuric acid treatment and characterized by using Powder-X ray diffraction (XRD), Scanning electron microscopy (SEM), Energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FT-IR).Temperature programmed ammonia desorption (NH3-TPD), Brunauer-Emmer-Teller (BET) surface area analysis. Modified dealuminat...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1960
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.80.11_1573